Simultaneous determination of total and immature neutrophil C-reactive protein in normal, diseased, and infected newborn infants
Krauel, J.; Salvado, A.; Mira, A.; Orellana, N.; Calvet, I.; Molina, V.; Lizarraga, I.
Anales Espanoles de Pediatria 27(4): 257-260
1987
ISSN/ISBN: 0302-4342 PMID: 3426018 Document Number: 291766
C. reactive protein and immature neutrophils/total neutrophils ratio are measured in 146 newborns. Three groups are considered: 37 healthy, 90 pathologic non infected and 19 bacteriologically confirmed infected newborns. Pathologies other than infection do not alter CRP nor I/T. Levels lower than 20 mg/l for CRP and 0.18 for I/T are considered normal. Both tests are considered very useful for neonatal infection diagnosis (p less than 0.001). CRP shows a higher sensitivity than I/T in neonatal infection diagnosis even in its initial period (84% versus 63%).