Forms of thalassemia identified in the city of São Paulo
De Araújo, J.T.; Ribeiro, V.S.; de Araújo, R.A.
Revista do Hospital das Clinicas 42(6): 267-272
1987
ISSN/ISBN: 0041-8781 PMID: 2458623 Document Number: 288236
From 1969 to 1985, 62 cases of thalassemia were studied: 25 of them were Th Beta+ form of the disease, 6 Th Betao one Th Delta Beta, 23 Th Hb S, 5 Th Hb C,1 Th Beta JRovigo and the 1 Th Hb Lepore. All the cases identified as Th Beta+ were characterized by the presence of Hb A1, whereas in the patients with Th Betao Hb A1 was absent. The cases with Th Hb S, association with sickle cell disease, showed a prevalence of Hb S and Hb F and an increase of Hb A2. Cases with Th Hb C also showed an association with the type Betao. The two cases identified at Th Hb FRovigo and Lepore occurred in the heterozygotical form.