Morphology and histogenesis of yolk sac tumors in the testis
Romanenko, A.M.; Persidskiĭ, I.V.
Arkhiv Patologii 49(2): 51-57
1987
ISSN/ISBN: 0004-1955 PMID: 3566556 Document Number: 287442
The differentiation of yolk sac tumor cells was similar to the processes of development of embryonic and extraembryonic endoderm during the first 7 wk after cleavage. Two ways of yolk sac tumor histogenesis are discussed; differentiation of embryonal carcinoma cells, and redifferentiation of the polypotent undifferentiated anaplastic seminoma cells. Histogenesis features described may be responsible for aggressive nature and high malignancy of yolk sac tumors.