Clinical and morphologic characteristics of low-renin hyperaldosteronism
Chikhladze, N.M.; Bronshteĭn, M.E.; Kazeev, K.N.
Kardiologiia 27(8): 21-24
1987
ISSN/ISBN: 0022-9040 PMID: 3316793 Document Number: 287049
A comparative assessment of the results of differential-diagnosis load tests and morphologic changes in adrenal tissue removed at surgery has been carried out in patients with arterial hypertension and low-renin hyperaldosteronism. Assessment of plasma aldosterone variations in response to load-tests has shown this parameter to be unrelated to the structure of aldosteroma, either before or after the test. Different patterns of aldosterone production control were demonstrated in cases of diffuse-nodular and adenomatous adrenal changes. The study has provided additional information on the pathogenesis of this condition.