Mobilization of different pools of glucose-incorporated calcium in pancreatic beta-cells after muscarinic receptor activation
Hellman, B.; Gylfe, E.; Bergsten, P.
Advances in Experimental Medicine and Biology 211: 325-341
1986
ISSN/ISBN: 0065-2598 PMID: 3300191 Document Number: 285456
Muscarinic receptor activation resulted in a biphasic mobilization of Ca2+ from isolated pancreatic islets. Glucose was essential for preparing the beta-cells to respond with the initial stimulatory phase. This effect seems to depend on the ability of the sugar to promote active sequestration of Ca2+ in the endoplasmic reticulum.
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