Cerebral glycolysis and glycogenolysis in diazinon treated animals
Husain, K.; Matin, M.A.
Arhiv Za Higijenu Rada i Toksikologiju 37(1): 29-34
1986
ISSN/ISBN: 0004-1254 PMID: 3813898 Document Number: 285287
Treatment with diazinon (40 mg/kg, i.p.) resulted in depletion of glycogen and increased activities of glycogen phosphorylase, phosphoglucomutase, hexokinase and lactate dehydrogenase in the brain of rats. The activity of glucose-6-phosphatase was not significantly changed. The level of lactic acid in the blood was raised, while that of pyruvic was not altered. The induced changes may be due to a compensatory mechanism providing extra energy on account of stimulatory effects in diazinon treated animals.