A trypsin inhibitor isolated from lymphatic leukemia cells
Hoser, G.; Kawiak, J.
Biomedica Biochimica Acta 45(9): 1127-1133
1986
ISSN/ISBN: 0232-766X PMID: 3814103 Document Number: 284441
A trypsin inhibitor from murine L 1210 lymphatic leukemia cells was isolated on QAE Sephadex A-50 and Trypsin-Sepharose 4B and purified about 197 times. It is a thermostable peptide, nonsensitive to changes in the pH range 2-10. It inhibits trypsin proteolytic activity against hemoglobin, azocaseine and trypsin esterase activity.
Document emailed within 1 workday
Related Documents
Trusova, N.F.; Tsigikian, T.A.; Shaternikov, V.A. 1973: Proteolytic activity and content of trypsin inhibitor in the blood serum of patients with leukemia Laboratornoe Delo 9: 546-549Ooka, T.; Hatano, Y.; Yamamoto, M.; Ogawa, K.; Saika, S. 1996: Protective effects of human urinary trypsin inhibitor against trypsin-induced relaxation in rat aorta Critical Care Medicine 24(11): 1903-1907
Aliev, R.E.; Godzhaev, N.M.; Popov, E.M. 1986: Conformational aspects of beta-trypsin interactions with substrates and pancreatic trypsin inhibitor. II. Structure of tetrahedral adducts and acylenzyme Molekuliarnaia Biologiia 20(2): 346-356
Ottmann, O.G.; Wassmann, B.; Hoelzer, D. 2002: Therapy of Philadelphia chromosome positive acute lymphatic leukemia (Ph+ ALL) with an inhibitor of abl-tyrosine kinase (Glivec) Medizinische Klinik 97(Suppl 1): 16-21
Li, M.; You, S.; Ge, W.; Ma, S.; Ma, N.; Zhao, C. 2003: Induction of T-cell immunity against leukemia by dendritic cells pulsed with total RNA isolated from leukemia cells Chinese Medical Journal 116(11): 1655-1661
Chrz, R.; Michalová, K.; Benesová, E.; Pössnerová, V. 1972: Finding of F body in blood cells of a woman with karyotype 46 XX with chronic lymphatic leukemia Sbornik Lekarsky 74(7): 218-221
Kuzumaki, N.; Moriuchi, T.; Kodama, T.; Kobayashi, H. 1976: Xenogenization of rat erythroid cells by lymphatic leukemia virus: its role in induction of autoimmune hemolytic anemia Journal of Immunology 117(4): 1250-1255
Kisilichina, D.G.; Lugovskaia, S.A.; Pochtar', M.E.; Naumova, E.V.; Biderman, B.V.; Sudarikov, A.B.; Nikitin, E.A.; Dolgov, V.V. 2012: The characteristics of evaluation of expression of ZAP-70 in tumor cells under b-cell chronic lymphatic leukemia using the flow cytofluorometry technique Klinicheskaia Laboratornaia Diagnostika 8: 47-52
Skórski, T.; Ratajczak, M.Z.; Kawalec, M.; Kawiak, J. 1991: Induction of immune resistance against L1210 lymphatic leukemia in mice after lethal irradiation and reconstruction with fetal liver cells Folia Histochemica et Cytobiologica 29(3): 121-124
Jagla, K.; Mucha, B.; Wilemska, A.; Marcinkowska, A.; Soszyńska, K.; Gołuszko, E.; Kremplewska, E.; Szadziewska, D.; Domaniewski, J. 1990: Trial application of transfection tests in feasibility studies for transforming DNA in white blood cells of patients with chronic lymphatic leukemia Polski Tygodnik Lekarski 45(21-22): 412-416
Pagnini, U.; Pacilio, C.; Florio, S.; Crispino, A.; Claudio, P.P.; Giordano, A.; Pagnini, G. 2000: Medroxyprogesterone acetate increases anthracyclines uptake in chronic lymphatic leukemia cells: role of nitric oxide and lipid peroxidation Anticancer Research 20(1a): 33-42
Hadnagy, C.; Marinca, E.; Macavei, I.; Sass, G. 1986: The simultaneous occurrence of chronic lymphatic leukemia with malignant tumors and the lymphatic reaction caused by malignant growths Folia Haematologica 113(5): 633-637
Takubo, T. 2010: Human urinary trypsin inhibitor Nihon Rinsho. Japanese Journal of Clinical Medicine 68(Suppl 7): 810-813
Takubo, T. 2005: Human urinary trypsin inhibitor Nihon Rinsho. Japanese Journal of Clinical Medicine 63(Suppl 8): 771-773
Li, Z.-j.; Chen, Z.-x.; Cen, J.-n.; He, J. 2006: Overexpression of tissue inhibitor of metalloprotease-2 promotes proliferation and infiltration of human monocytic leukemia cells Zhonghua Yi Xue Za Zhi 86(34): 2409-2412
Nagaya, H.; Satoh, H.; Maki, Y. 1990: Possible mechanism for the inhibition of acid formation by the proton pump inhibitor AG-1749 in isolated canine parietal cells Journal of Pharmacology and Experimental Therapeutics 252(3): 1289-1295
Oyama, T.; Miyahara, T.; Ishihara, H.; Yao, M.; Honda, K. 1983: Effect of urinary trypsin inhibitor MR-20 in shock Progress in Clinical and Biological Research 111: 283-291
Chauhan, U.P. 1989: Glutathione as an inhibitor of trypsin induced proteolysis Indian Journal of Experimental Biology 27(5): 472-473
Hibasami, H.; Sakurai, M.; Maekawa, S.; Nakashima, K. 1987: Methylthiopropylamine, a potent inhibitor of spermidine synthase and its antiproliferative effect on human lymphoid leukemia Molt 4B cells Anticancer Research 7(6): 1213-1216
Urbańczyk, J.; Zygadlo, H. 1973: Diagnostic difficulties in a case of concommittance or transformation of chronic granulocytic leukemia into lymphatic leukemia Przeglad Lekarski 30(6): 527-529