D-penicillamine and collagen
Camus, J.P.; Koeger, A.C.
Annales de Biologie Clinique 44(3): 296-299
1986
ISSN/ISBN: 0003-3898 PMID: 3538948 Document Number: 284423
D-penicillamin is widely used for the treatment of various diseases, such as cystinuria. Wilson's disease or rheumatoid arthritis. It is an osteolathyrogenic agent. This effect may explain some side-effects such as fetal dysplasias, wound healing defects, skin lesions, obliterative bronchiolitis, auto-immune abnormalities. Conversely the collagen effects of D-Penicillamin explain its use in various fibrosis states such as progressive systemic sclerosis, liver or lung fibrosis.
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