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Renal excretion of total porphyrins and hippuric acid in rats

Gartzke, J.; Burck, D.

Journal of Clinical Chemistry and Clinical Biochemistry 24(9): 637-639

1986

ISSN/ISBN: 0340-076X
PMID: 3772308
Document Number: 284310
The amounts of total porphyrins, hippuric acid and creatinine, excreted in urine by adult male Wistar rats, exhibited normal distributions for hippuric acid and creatinine, but a bimodal distribution for total porphyrins. This typical distribution of total porphyrins was still observed when creatinine was used as reference parameter. In biochemical and toxicological experiments in rats, the tested parameters should be therefore be investigated for homogeneity.

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