Lymphocyte subpopulations in alopecia areata
Calandria, L.; Paciel, J.; Bruno, J.; Martini, M.; Vignale, R.; Civila, E.
Medicina Cutanea Ibero-Latino-Americana 14(3): 163-165
1986
ISSN/ISBN: 0210-5187 PMID: 3526043 Document Number: 284269
Subsets of peripheral blood lymphocytes were studied in 19 patients with alopecia areata. The results shows: a decreased Tm/Tg ratio, decreased number of OKT4+ cells, increased OKT8+ cells, decreased OKT4+/OKT8+ cell ratio. Total lymphocytes, T cells, Tm cells, Tg cells, T DR+ cells and B lymphocytes were normal. The results are similar to those founded in autoimmune diseases and suggest the existence of an immunopathogenic mechanism in these disease.