Chronic lymphocytic leukemia in the dog: 22 cases (1974-1984)

Leifer, C.E.; Matus, R.E.; Leifer, C.E; Matus, R.E

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Chronic lymphocytic leukemia in the dog: 22 cases (1974-1984)

Leifer, C.E.; Matus, R.E.

Journal of the American Veterinary Medical Association 189(2): 214-217

1986

ISSN/ISBN: 0003-1488

PMID: 3755718

Document Number: 284241

Chronic lymphocytic leukemia was diagnosed in 22 dogs. Diagnosis was based primarily on detection of lymphocytosis and bone marrow infiltration with small lymphocytes similar to those seen in the blood. More than 50% of the dogs had monoclonal gammopathy, and, of these, 40% had monoclonal light-chain (Bence Jones) proteinuria. Hyperviscosity syndrome was observed occasionally. Most dogs were treated with chemotherapy. For the 17 dogs treated greater than or equal to 30 days, the survival times ranged from 30 to 1,000 days.