Complete remission obtained in advanced testicular cancer treated by etoposide (NK-171)
Babaya, K.; Tsumatani, K.; Natsume, O.; Yoshie, T.; Kubota, K.; Ozono, S.; Hirao, Y.; Okajima, E.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 13(3 Part 1): 604-607
1986
ISSN/ISBN: 0385-0684 PMID: 2420282 Document Number: 284220
A 38-year-old man was admitted to Nara Medical University Hospital on Feb.7,1983, because of swelling of the scrotal contents on the right side and elevated serum AFP, beta-HCG and LDH suggestive of testicular tumor. Right orchiectomy was carried out and a pathological diagnosis of embryonal cell carcinoma of the right testis (pT3N0M1) was made. The patient, upon evidence of multiple pulmonary metastases, was treated with a combination chemotherapy of cis-Diamminedichloroplatinum, vincristine and peplomycin. After three courses of combination chemotherapy, pulmonary metastases were decreased, but their foci persisted. The patient was then treated with Etoposide 62 mg/m2 daily for 5 days every three weeks, and after this course, complete remission of pulmonary metastases was obtained. The patient recieved 3 courses of Etoposide and retroperitoneal lymph node dissection, and has since shown no evidence of disease for 2 years and 4 months after surgery.