A case of remission of multiple retroperitoneal lymph node relapse in small cell lung cancer treated with oral etoposide
Fujii, S.; Masakane, I.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 18(2): 297-300
1991
ISSN/ISBN: 0385-0684 PMID: 1847031 Document Number: 369738
A 57-Year-old male with small cell lung cancer had been treated by cisplatin and etoposide. After these chemotherapies he relapsed with the primary site and multiple brain metastases followed by chest irradiation (50 GY) and cranial radiotherapy (40 GY). Though these sites were regressive, abdominal tumor was detected. So, abdominal CT showed multiple retroperitoneal lymphnode swellings and abdominal wall involvement without liver metastasis. After cisplatin and etoposide were administered intravenously, he was treated with etoposide (150 mg/body days 1-4) orally every month. Retroperitoneal lymphnode swellings were remarkably regressed with oral administration of etoposide. It is conceivable that etoposide is one of the useful salvage chemotherapies of relapsed small cell lung cancer, even treated orally.