Hepatitis D infectivity profile among hepatitis B infected hospitalised patients in Calcutta
Bhattacharyya, S.; Dalal, B.S.; Lahiri, A.
Indian Journal of Public Health 42(4): 108-112
1998
ISSN/ISBN: 0019-557X PMID: 10389522 Document Number: 283987
This study was carried out at Nil Ratan Sarkar Medical College, Calcutta from December 1993-95 among 450 patients with hepatic and nonhepatic disorders and 100 normal individuals. The study was conducted to examine the association between serum Hepatitis B surface antigen (HBsAg) and Delta virus (HDV) antigen, and different clinical disorders. Serum was tested for bilirubin and serum glutamic pyruvic transaminase (SGPT) and detection of HBsAg and HDV antigen. Results showed that the presence of HBsAg was found highest in cirrhosis of liver (42.3%), followed by leukemia (32.1%), hepatitis (29.1%), and jaundice (26%). About 65% of HBsAg positive jaundiced patients had a serum bilirubin level of more than 2mg/dl, with a mean SGPT level of 488iu/l. Only two cases were positive for HDV antigen among 60 HBsAg positive jaundice patients, indicating a lower prevalence rate of infection. It also showed that the mean SGPT level was directly proportional to the serum bilirubin level. Age distribution varied from 19.5% to 23.6% among extreme ages, and only 24.8% among the sexually active group.