Disseminated intravascular coagulation syndrome (DIC) in stomach and intestinal cancer
Pavlovskiĭ, D.P.
Voprosy Onkologii 32(2): 37-42
1986
ISSN/ISBN: 0507-3758 PMID: 3485857 Document Number: 283795
Hemostasis was studied in 70 patients with gastric or intestinal cancer. Pronounced imbalance in blood coagulation was established, resulting in chronic disseminated intravascular coagulation (DIC) syndrome in 55.7 and thrombophilia--in 20% of cases. Advancement of tumor to stage IV was followed by development of stage II (subacute) DIC syndrome. The syndrome was frequently manifested by thrombohemorrhagic complications which occurred in 14.5% of cancer patients (autopsy data). It was inferred that timely treatment of malignancies, early administration of heparin, fibrinolysis--activating drugs and deaggregants are pathogenetically justified means for prevention and treatment of DIC syndrome.