Update on prolactin
Dupont, G.; Paulson, G.
Revue Francaise de Gynecologie et d'Obstetrique 81(8): 419-421
1986
ISSN/ISBN: 0035-290X PMID: 3764300 Document Number: 282264
Normal serum prolactin levels range from 5 to 20 ng/ml (circadian rhythm, effect of stress, relation with estrogen secretion). Neuroleptics increase serum prolactin levels. Normal concentrations are restored within 24 to 48 hours of discontinuation of the drug. When neuroleptics are given for a long period of time, serum prolactin concentrations fall gradually to low levels. There is no conclusive evidence that prolactin plays a role in breast tumors in women. Epidemiologic studies have shown that neuroleptics are not responsible for increased incidences of these tumors.
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