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Analysis of the immunochemical purity of modern influenza vaccines

Zhebrun, A.B.; Polianskaia, N.Iu.; Bichurina, M.A.; Rozaeva, N.R.; Fridman, E.A.

Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 1986(10): 56-59

1986

ISSN/ISBN: 0372-9311
PMID: 3799103
Document Number: 281875
Corpuscular influenza vaccines have been found to contain chick embryo antigens differing from ovalbumin in their antigenic, immunogenic, and allergenic properties. The study has revealed that host antigens are present in vaccines in the form of free contaminants and as substances incorporated into viruses. The vaccine prepared by the method of sorption-elution on red blood cells with subsequent gel chromatography is characterized by the highest antigenic purity.

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