Pathogenesis and diagnosis of dysovarian cardiomyopathy
Karpov, R.S.; Slepushkin, V.D.; Mordovin, V.F.; Zykova, V.A.; Khavinson, V.K.
Terapevticheskii Arkhiv 58(11): 70-73
1986
ISSN/ISBN: 0040-3660 PMID: 3824194 Document Number: 280031
Altogether 78 patients with dysovarian cardiomyopathy were examined, of them in 19 patients the FSH, LH, prolactin, estradiol and testosterone levels were studied. Function of the epiphysis was evaluated by melatonin excretion with urine in 46 patients. Correlation of the metabolism of sex hormones and function of the epiphysis was shown. It was assumed that the effect of disturbance of the metabolism of sex hormones on the myocardium was expressed in change of electrolyte metabolism. A new method was proposed for the diagnosis of dysovarian cardiomyopathy with the help of a pharmacological drug epithalamin whose administration returned the level of the gonadotropic hormones to normal and was accompanied by positive time course of a clinical picture of disease.