Blood and plasma viscosity in experimentally induced hyper- and hypo-fibrinogenaemia
Pola, P.; Flore, R.; Tondi, P.
International Journal of Tissue Reactions 8(4): 333-336
1986
ISSN/ISBN: 0250-0868 PMID: 2943690 Document Number: 279667
For some time now fibrinogen has been attributed considerable importance in influencing blood and plasma viscosity. This paper attempts to experimentally confirm this statement in vivo: two groups of arteriopathic patients were selected for investigating viscosity in hyper- and hypo-fibrinogenaemia induced by PTA and a cycle of fibrinolytic treatment with urokinase respectively. Although fibrinogenaemia exhibited highly significant changes under such conditions, there was no important change in viscosity. Probably the role of fibrinogen in influencing viscosity has been overestimated in the past and it is likely that there are other more important factors.