A drop in &quot;apparent&quot; blood viscosity due to administration of high-molecular polymer capable of augmenting viscosity

Grigorian, S.S.; Sokolova, I.A.; Shakhnazarov, A.A.; Timkina, M.I.; Proskurin, S.G.; Priezzhev, A.V.; Grigorian, S.S; Sokolova, I.A; Shakhnazarov, A.A; Timkina, M.I; Proskurin, S.G; Priezzhev, A.V

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A drop in "apparent" blood viscosity due to administration of high-molecular polymer capable of augmenting viscosity

Grigorian, S.S.; Sokolova, I.A.; Shakhnazarov, A.A.; Timkina, M.I.; Proskurin, S.G.; Priezzhev, A.V.

Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova 91(1): 46-52

2005

ISSN/ISBN: 0869-8139

PMID: 15773579

Document Number: 584528

Influence of a high-molecular compound capable of augmenting viscosity, namely: polyethylene oxide Polyox WSR-301, on hemodynamic parameters in rat mesenteric microvessels was investigated. A substantial decrease in the arteriolar hemodynamic resistance caused by the polymer was revealed. Special research has shown that this reaction is not connected with a vasodilatation and, therefore, is caused by a reduction in the "apparent" viscosity of the blood, i.e., it is a consequence of changed properties of the blood flow.