A case of adiposis dolorosa: lipid metabolism and hormone secretion

Taniguchi, A.; Okuda, H.; Mishima, Y.; Nagata, I.; Oseko, F.; Hara, M.; Otsu, A.; Kataoka, K.; Kono, T.; Imura, H.

International Journal of Obesity 10(4): 277-281

1986


ISSN/ISBN: 0307-0565
PMID: 3771092
Document Number: 278251
The present report describes a 53-year-old non-obese man with adiposis dolorosa whose pain was dramatically relieved by the intravenous injection of lidocaine. The patient showed a paradoxical response of growth hormone to thyrotropin-releasing hormone. In addition, in-vitro studies on adipose tissue metabolism revealed the reduced glucose conversion to neutral glycerides in painful adipose tissue. These abnormalities may be related in some ways to the pathogenesis of this disorder.

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