An unusual case of POEMS syndrome
Sigler, E.; Modai, D.; Zaidenstein, R.; Golik, A.; Marcus, E.L.; Cohen, N.
Israel Journal of Medical Sciences 22(12): 906-908
1986
ISSN/ISBN: 0021-2180 PMID: 3570737 Document Number: 276712
A 58-year-old woman presented with a history of premature onset of menopause, longstanding hepatosplenomegaly, monoclonal gammopathy, lower limb polyneuropathy of recent onset, diabetes mellitus, excessive perspiration and leg edema. Polyneuropathy and excessive perspiration improved following a course of prednisone and melphalan. The clinical and pathophysiological features fit the rare entity known as POEMS syndrome.