Usefulness of cerebral computed axial tomography in the early diagnosis of tuberous sclerosis
Jordán, J.; Rodríguez, C.; Ortiz, P.; Pérez Higueras, A.; Pascual-Castroviejo, I.
Anales Espanoles de Pediatria 24(3): 165-170
1986
ISSN/ISBN: 0302-4342 PMID: 3706922 Document Number: 273964
Authors describe twelve children with diagnosis of tuberous sclerosis (TS) within the first year. All children had seizures, being infantile spasms in 7 cases (58%). All but one showed severe mental retardation. Hypopigmented patches in 2 (16.6%) and retinal phakoma in one case (8.3%). Skull Rx were normal in all cases, while the CT showed early intracranial calcifications in the 100% of the patients and areas of hypodensity in the 50%. The CT is the most useful test for the early diagnosis of TS when the clinical diagnosis has not been firmly established.