Osteomyelitis in Gaucher disease
Bell, R.S.; Mankin, H.J.; Doppelt, S.H.
Journal of Bone and Joint Surgery. American Volume 68(9): 1380-1388
1986
ISSN/ISBN: 0021-9355 PMID: 3782210 Document Number: 273867
A relatively common complication of Gaucher disease, the so-called crisis, frequently is difficult to differentiate from acute osteomyelitis. We reviewed the cases of forty-nine patients with Gaucher disease who were treated at the Massachusetts General Hospital and found that elelven patients had required admission to the hospital for an acute symptom complex that represented either a crisis or an infection. Five of the patients proved to have acute hematogenous osteomyelitis. The delayed diagnosis of the infection in three of the patients with osteomyelitis led to an unsatisfactory outcome.