Possible danger of rapid intravenous amiodarone in re-entry tachycardia in subjects with Wolff-Parkinson-White syndrome
Vitale, P.; De Stefano, R.; Auricchio, A.
Giornale Italiano di Cardiologia 16(11): 969-974
1986
ISSN/ISBN: 0046-5968 PMID: 3556935 Document Number: 272869
In order to control a re-entrant tachycardia in a patient with Wolff-Parkinson-White syndrome, intravenous Amiodarone (5 mg/Kg per min.) was administered. The drug caused a blood pressure fall, a sympathetic drive and an increase of frequency up to a value of 187/min. An atrial fibrillation with rapid ventricular response in pattern of pseudo-ventricular tachycardia intervened by conduction on accessory pathway. In order to avoid the risk of ventricular fibrillation it is suggested to be wary in the use of rapid intravenous Amiodarone when associated with Wolff-Parkinson-White syndrome.