Primary hyperparathyroidism in a dog: biochemical, bone histomorphometric, and pathologic findings
Weir, E.C.; Norrdin, R.W.; Barthold, S.W.; Meuten, D.J.; Pond, M.J.; Insogna, K.L.
Journal of the American Veterinary Medical Association 189(11): 1471-1474
1986
ISSN/ISBN: 0003-1488 PMID: 3804843 Document Number: 272413
An adult Keeshond had clinical signs associated with hypercalcemia, including inappetence, polyuria, polydipsia, and vomiting. Blood biochemical findings and urinary clearance studies were consistent with a diagnosis of primary hyperparathyroidism. Histomorphometric analysis of trabecular bone in an iliac crest biopsy indicated increased bone remodeling activity. Surgical exploration of the neck revealed an oval mass, which was removed by blunt dissection. Histologic diagnosis was parathyroid gland adenoma. The dog died because of renal failure on the eighth postoperative day. This report defines primary hyperparathyroidism in the dog, thus facilitating diagnosis for the veterinary clinician.