Kallikrein as a modulator of serotoninergic and bradykininergic myotropic reactions in the small intestine
Vasil'ev, V.N.; Medvedev, M.A.
Biulleten' Eksperimental'noi Biologii i Meditsiny 101(1): 7-9
1986
ISSN/ISBN: 0365-9615 PMID: 3632910 Document Number: 270867
The effect of 0.01 U/ml of kallikrein on serotonin and bradykinin contractile action in the isolated intestinal segment has been described. The character of myotropic reactions was shown to change in accordance with the anatomical localization of the intestinal segment. Sensitivity to serotonin and bradykinin increases in duodenum segments and decreases in jejunum and ileum segments. Kallikrein is supposed to serve as a modulator of intestinal serotonin and bradykininergic myotropic reactions.