Clinical trial of high doses of Bay I 7433 (Copovithane)
Ucci, G.; Riccardi, A.; Danova, M.; Faravelli, M.; Salvini, P.; Girino, M.
Drugs under Experimental and Clinical Research 12(8): 713-715
1986
ISSN/ISBN: 0378-6501 PMID: 3530678 Document Number: 270779
Bay i 7433 (Copovithane) is a biological response modifier with antitumour activity in vivo, but no cytotoxic or cytostatic effect in vitro. A clinical trial of the compound at doses of 15g/m2/week was carried out for six weeks in 10 patients with various forms of cancer. Tolerance was good: no systemic toxicity was observed but local inflammation occurred in two cases at the site of injection. No objective antitumour response was observed.
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