Lipiodolized angiography in hepatocellular carcinomas. Contribution of iodine-131-labelled lipiodol
Raoul, J.L.; Duvauferrier, R.; Bourguet, P.; Bretagne, J.F.; Coornaert, S.; Darnault, P.; Deugnier, Y.; Herry, J.Y.; Gastard, J.
Journal de Radiologie 67(11): 797-801
1986
ISSN/ISBN: 0221-0363 PMID: 3027321 Document Number: 270335
Twelve patients with hepatocellular carcinoma and cirrhosis were investigated by Lipiodol injection into the hepatic artery. A CT scan was done 4-6 days later. Lipiodol was retained by hepatic tumors in each case. This method emphasized the extension of the carcinoma and allowed to discover daughter tumors. I131-lipiodol was also injected in 4 of the 12 patients and then its biodistribution was evaluated. At the 6th hour after injection, I131-lipiodol was detected by scintigraphy over the liver (74-91 percent) and over the lungs (9-16 percent) only. The tumor to normal liver pixel count ratio was about 5. These results indicate that there is a preferential arterial blood flow towards the hepatic tumors, and that we can consider a therapeutic use of I131-Lipiodol in hepatocellular-carcinoma.