Skeletal muscle in uremia
Janda, J.
Ceskoslovenska Patologie 22(2): 111-115
1986
ISSN/ISBN: 1210-7875 PMID: 3731294 Document Number: 269513
A post mortem histochemical study of girdle muscles was performed in 54 persons having died of uremia (42 of them treated by long-term dialysis). The most important findings was an atrophy of 2B-type fibres which was combined with osteomalacia in 36% dialysed patients. An etiopathogenetical discussion included toxic effects of parathormone and aluminium ions, disturbance of glycolysis and uremic carnitine deficiency.
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