Ostium stenosis of both coronary arteries and latent hypothyroidism as sequelae of radiotherapy in Hodgkin disease
Stegaru-Hellring, B.; Keller, H.; Bode, H.; Usadel, K.H.; Wallwork, J.
Zeitschrift für Kardiologie 74(8): 485-488
1985
ISSN/ISBN: 0300-5860 PMID: 4050000 Document Number: 265262
Premature arteriosclerosis following irradiation is a known experimental and clinical phenomenon. Although the heart was once considered a relatively radioresistant organ, now all components, including the coronary arteries, are recognised as possible targets of radiation injury. We present a 40-year-old women who received extensive neck and thoracic radiation for treatment of Hodgkin's disease. Ten years later she developed severe coronary artery disease with ostium stenosis of the left and right coronary arteries, as well as subclinical hypothyroidism.