Glucose increases cytosolic Ca2+ activity in pancreatic islet cells
Deleers, M.; Mahy, M.; Malaisse, W.J.
Biochemistry International 10(1): 97-103
1985
ISSN/ISBN: 0158-5231 PMID: 3885954 Document Number: 265049
Isolated cells prepared from rat pancreatic islets were labelled with the tetraacetoxymethyl ester of the fluorescent Ca2+ indicator quin-2. An increase in the extracellular concentration of glucose provoked a rapid and sustained increase in the fluorescence of the labelled cells. This indicates that glucose increases cytosolic Ca2+ activity in pancreatic islet cells.
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