The effect of infusion of various peptide antisera on vasodilatation in the cat common carotid vascular territory

Goadsby, P.J.; Macdonald, G.J.

Clinical and Experimental Neurology 21: 115-121

1985


ISSN/ISBN: 0196-6383
PMID: 2436837
Document Number: 264316
Electrical stimulation of the locus coeruleus leads to a frequency-dependent vasoconstriction in the internal carotid vascular bed and a frequency-dependent vasodilatation in the external carotid vascular bed. This latter dilator response is mediated via the facial nerve, and then more peripherally through the pterygopalatine and otic ganglia, and employs the neuropeptide vasoactive intestinal polypeptide (VIP) as its transmitter.

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