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Niridazole as an adjunct to "conventional" immunosuppression in kidney allograft transplantation. Long-term follow up

Orlowski, T.; Smogorzewski, M.; Kurkus, J.

Archivum Immunologiae et Therapiae Experimentalis 33(6): 797-801

1985

ISSN/ISBN: 0004-069X
PMID: 3914251
Document Number: 261828
To assess the value of niridazole as adjuvant immunosuppressant to conventional steroid and azathioprine therapy, a prospective randomized clinical study in 26 cadaver kidney recipients had been performed. No beneficial effect was observed on the kidney graft survival with the addition of niridazole. Neither was there any additional immunosuppressive action demonstrated in the serum of the patients in this group. On the basis of our limited clinical experience niridazole can not be recommended as an adjunct agent for kidney graft recipients.

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