Calcitonin antibodies in experimental diabetes mellitus
Kulikova, L.I.; Tsvetkov, V.S.; Bondarenko, M.F.; Gordienko, S.P.
Biulleten' Eksperimental'noi Biologii i Meditsiny 99(4): 422-424
1985
ISSN/ISBN: 0365-9615 PMID: 3886041 Document Number: 258419
Antibodies to calcitonin appear in blood of rats with experimental alloxan diabetes. This phenomenon is observed only under high blood sugar. At the stage of latent diabetes, i.e. during alloxan administration to the body and low blood sugar no antibodies to calcitonin are detected. It is possible that appearance of autoantibodies to calcitonin is one of pathogenetic factors of hyperglycemia development in rats with alloxan diabetes.