Hyperinsulinemia in tube-fed hypophysectomized rats bearing hypothalamic lesions

Han, P.W.; Frohman, L.A.

American Journal of Physiology 219(6): 1632-1636

1970


ISSN/ISBN: 0002-9513
PMID: 4991955
Document Number: 25771
Twenty-one hypophysectomised rats bearing bilateral hypothalamic lesions and 10 hypophysectomised controls were tube fed on equal amounts of a liquid diet for 28 days. Plasma insulin was consistently higher in the first rats beginning with the 5th day after operation. Plasma glucose also was slightly higher on most days. Pancreatic insulin concentration was identical.

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