Sodium permeability of erythrocyte membranes of essential hypertension patients with and without a hereditary predisposition to the disease
Postnov, I.I.; Liusov, V.A.
Kardiologiia 25(1): 47-50
1985
ISSN/ISBN: 0022-9040 PMID: 3981861 Document Number: 257488
Recording the maximum rate of Na/Li-antitransportation, the permeability of erythrocyte membranes was studied in patients with stage II and III essential hypertension whose parents had arterial hypertension (44 patients) or had the normal arterial pressure (20). In hypertensive patients with hereditary liability to the disease, the erythrocyte membrane permeability was higher (533 +/- 23 mumol per 1 1 of cells per hour) than in hypertensive patients without such predisposition (443 +/- 43 mumol per 1 1 of cells per hour; p less than 0.05). Arterial hypertension in patients with essential hypertension with hereditary predisposition to the disease developed five years earlier (p less than 0.05) as against hypertensive patients without aggravated heredity. The erythrocyte membrane permeability in men versus women showed no difference in both stage II and III essential hypertension.