Determination of catalytic constants of an acetic acid-sodium acetate buffer in comparison with amoxicillin trihydrate

Girona, V.; Bolós, J.; Castillo, M.; García, S.

Il Farmaco; Edizione Pratica 40(7): 237-241

1985


ISSN/ISBN: 0430-0912
PMID: 4029369
Document Number: 256764
The catalytic constants of the amoxicillin hydrolysis reaction for the species participating in the degradation of this antibiotic in the presence of an acetic acid-acetate regulating mixture have been calculated. It is concluded that the use of this buffer has advantages over the citric acid-citrate buffer since the catalytic constants are lower.

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