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Birth defects surveillance study

Patel, Z.M.; Adhia, R.A.

Indian Journal of Pediatrics 72(6): 489-491

2005

ISSN/ISBN: 0019-5456
PMID: 15985737
DOI: 10.1007/bf02724426
Document Number: 255452
Objective : To study the overall frequency of congenital malformations in a city hospital in the first three days of life. Methods: 17,653 consecutive newborns were examined and diagnosed at a maternity hospital by pediatricians and geneticists. Relevant information was documented on a predesigned proforma and analyzed. Results: Of the 17,653 births 294 (1; 6%) had major malformations and 1400 (7.92%) had minor malformations. Amongst 17,653 births 328 (1.8%) were stillbirths. Malformations were highest in this group. Polygenic traits accounted for 45.1% while chromosomal etiology was found in 4%. A genetic basis was found in 65.4% of cases. Conclusion: With emphasis on "small family" norms & population control it is necessary to identify malformations so that Interventional programmes can be planned.

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Birth defects surveillance study

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