A syllectrometric method to study erythrocyte aggregation
Pieragalli, D.; Forconi, S.; Guerrini, M.; Acciavatti, A.; Galigani, C.; Del Bigo, C.; Di Perri, T.
La Ricerca in Clinica e in Laboratorio 15(Suppl 1): 79-86
1985
ISSN/ISBN: 0390-5748 PMID: 3929369 Document Number: 255162
The authors show a new method to study erythrocyte aggregation; the results of in vitro study, obtained by modification of several parameters (hematocrit, immunoglobulins, fibrinogen concentrations), are exposed. The authors did not find in vivo correlations between MAE and hemorheological parameters in different diseases; they found low MAE values only in myelomatous subjects. Adding erythrocytes from healthy donors to myelomatous plasma and vice versa, they found low MAE values only in samples containing erythrocytes and plasma from myeloma. These results suggest that many factors, not only erythrocyte aggregability, contribute to determine MAE (Mean Aggregation Entity).