Two cases of paragangliomas of the cauda equina--case reports and review of the literature

Minase, T.; Kaku, T.; Dempo, K.; Ohtani, S.; Mori, M.; Ohnishi, H.; Kobayashi, H.

Gan no Rinsho. Japan Journal of Cancer Clinics 31(8): 1012-1017

1985


ISSN/ISBN: 0021-4949
PMID: 4032767
Document Number: 255101
Paragangliomas are tumors arising in the paraganglia and rarely occurring in the cauda equina. We report two cases of paraganglioma arising in this region. The tumors exhibited a typical "Zellballen" pattern, and immunohistochemical studies were positive for neuron-specific enolase, but negative for S-100 protein and glial fibrillary acidic protein. Electron microscopic studies confirmed electron-dense neurosecretory types of granules in the tumor cells. Only 23 cases of paragangliomas in this region have been previously reported. A brief review of the literature is included.

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