HLA-DR in rheumatoid arthritis

Iakovleva, D.B.; Benevolenskaia, L.I.; Orlov-Morozov, A.V.; Kalinina, N.M.

Terapevticheskii Arkhiv 57(8): 80-82

1985


ISSN/ISBN: 0040-3660
PMID: 3934781
Document Number: 254953
The authors describe the results of HLA-DR typing of 80 patients with rheumatoid arthritis (RA). The patients showed accumulation of HIA-DR (51.25% versus 28.9% in the control), with the relative risk being 2.58. The interrelationship is demonstrated between the clinical picture of RA and HIA-DR antigens: a statistically significant accumulation of HIA-DR4 in the seropositive patterns according to the RF of RA as compared with the seronegative pattern and primary demonstration of HIA-DR3 in RA with the systemic manifestations as compared with the articular pattern.

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