Thymic factor therapy for herpetic keratitis
Pivetti-Pezzi, P.; De Liso, P.; Tamburi, S.; Luzi, G.; Sirianni, M.C.; Palmisano, L.; Aiuti, F.
Annals of Ophthalmology 17(6): 327-331
1985
ISSN/ISBN: 0003-4886 PMID: 3893286 Document Number: 254546
Thirty patients with herpetic keratitis were allocated to a double-blind trial with either local treatment plus placebo (control group) or local treatment plus thymostimulin (TS group). The follow-up at 24 months demonstrated a significant reduction of recurrence rate among patients receiving thymostimulin, along with a significant increase of sheep rosette-forming cells (E rosette). Furthermore, among patients with superficial keratitis, thymostimulin treatment resulted in a significantly quicker corneal re-epithelization than placebo. Thymostimulin seems to be a safe and helpful drug in the management of herpetic keratitis.