Attempts to modify treatment of intestinal capillariasis
Basaca-Sevilla, V.; Cross, J.H.
Southeast Asian Journal of Tropical Medicine and Public Health 16(4): 546-548
1985
ISSN/ISBN: 0125-1562 PMID: 3835695 Document Number: 253624
Attempts to reduce the standard treatment of intestinal capillariasis of 200 mg mebendazole twice daily for 20 days were not successful. Two of 13 patients given mebendazole at single daily dosages of 500 mg per day for 16 days relapsed 3 to 6 months after treatment. Attempts to reduce the treatment to 14 days were even less satisfactory in that 4 of 8 patients treated experienced relapses 2 to 9 months later. Since intestinal capillariasis can be fatal it is recommended to continue the use of the standard schedule of 400 mg mebendazole daily for 20 days for new cases and 30 days for relapsed cases until a more effective drug is available.