Isoniazid acetylation in Gilbert's syndrome
Pereira-Filho, R.A.; Sevá-Pereira, A.; de Magalhães, A.F.
Arquivos de Gastroenterologia 22(4): 172-175
1985
ISSN/ISBN: 0004-2803 PMID: 3837656 Document Number: 253004
Phenotyping of isoniazid acetylators in 19 Caucasoid patients with Gilbert's syndrome was achieved by evaluating the percentual of acetylisoniazid in the urine. The proportion of slow acetylators among the patients with Gilbert's syndrome was similar to those found among Caucasoids of control group. The conclusion was that Gilbert's syndrome doesn't interfere in the hepatic capacity of isoniazid acetylation.