Development of a rubella vaccination strategy: contribution of a rubella susceptibility study of women of childbearing age in Kyrgyzstan, 2001

Malakmadze, N.; Zimmerman, L.A.; Uzicanin, A.; Shteinke, L.; Caceres, V.M.; Kasymbekova, K.; Sozina, I.; Glasser, J.W.; Joldubaeva, M.; Aidyralieva, C.; Icenogle, J.P.; Strebel, P.M.; Reef, S.E.; Malakmadze, N; Zimmerman, L.A; Uzicanin, A; Shteinke, L; Caceres, V.M; Kasymbekova, K; Sozina, I; Glasser, J.W; Joldubaeva, M; Aidyralieva, C; Icenogle, J.P; Strebel, P.M; Reef, S.E

doi:10.1086/421018

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Development of a rubella vaccination strategy: contribution of a rubella susceptibility study of women of childbearing age in Kyrgyzstan, 2001

Malakmadze, N.; Zimmerman, L.A.; Uzicanin, A.; Shteinke, L.; Caceres, V.M.; Kasymbekova, K.; Sozina, I.; Glasser, J.W.; Joldubaeva, M.; Aidyralieva, C.; Icenogle, J.P.; Strebel, P.M.; Reef, S.E.

Clinical Infectious Diseases An Official Publication of the Infectious Diseases Society of America 38(12): 1780-1783

2004

ISSN/ISBN: 1537-6591

PMID: 15227627

DOI: 10.1086/421018

Document Number: 251464

To contribute to the development of a rubella vaccination strategy, we conducted a study to determine age-specific susceptibility among women aged 15-39 years by testing for rubella-specific IgG antibodies. Of 964 women, 13% were found to be susceptible to rubella. Significantly higher susceptibility among women >25 years old was observed. Susceptibility data are important but are not sufficient to develop a vaccination strategy. After considering all available information, we suggested vaccination of women aged <35 years and selective vaccination of older women who were planning pregnancy.