Clinical and functional sequelae of bronchiolitis
Verini, M.; Bosco, F.; Flacco, L.; Ribaldi, R.; Marchioni, A.; Chiarelli, F.; Vecchiet, L.; Morgese, G.
La Pediatria Medica e Chirurgica Medical and Surgical Pediatrics 7(3): 405-410
1985
ISSN/ISBN: 0391-5387 PMID: 3837201 Document Number: 251434
The authors carried out a follow-up on twenty-five children, affected with bronchiolitis in the early years of life, at seven years of age, in order to evaluate their clinical status and pulmonary function. Their parents were questioned about diseases of the small airways following to acute bronchiolitis. PRIST and RAST were effected in fourteen children; an evaluation of the pulmonary function with spirometry, flow-volume curve and body-plethysmography was done in every child. Then the flow-volume curve was repeated after bronchial provocation test with exercise (free running). Abnormalities of the pulmonary function at resting significant for small airways' obstruction were observed. A great number of children with bronchial hyperreactivity (60%) was observed after bronchial provocation test with exercise, particularly in those with genetic predisposition; 6/14 (43%) showed sensitization to many inhalant allergens, without correlation with genetic predisposition, clinical sequences and bronchial hyperreactivity.