Characteristics of monocyte functional activity in acute viral hepatitis
Filev, L.V.; Popov, V.G.; Volchek, I.V.; Enokhin, S.F.; Sheĭpak, L.N.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 8: 61-65
1985
ISSN/ISBN: 0372-9311 PMID: 4060955 Document Number: 250687
The functional activity of monocytes in acute viral hepatitis has been studied. As revealed by the NBT test, circulating monocytes are damaged by viruses and/or virus-containing complexes. Proceeding from this fact, the percentage of monocytes containing virus inclusions should be considered as the percentage of monocytes damaged by the virus, and the coefficient of the inclusion of viral particles should be considered as the quantitative characteristic of the viral damage of monocytes. The decrease of the percentage of functionally active monocytes creates suitable conditions for the persistence of the virus in monocytes and for the disease to become chronic.