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Lipid peroxidation and the functioning of the Ca pump of the sarcoplasmic reticulum of skeletal muscle in hypercholesterolemia

Timofeev, A.A.; Kuz'mina, I.L.; Azizova, O.A.; Chernysheva, G.V.

Biulleten' Eksperimental'noi Biologii i Meditsiny 99(1): 55-57

1985

ISSN/ISBN: 0365-9615
PMID: 2578298
Document Number: 250552
During prolonged hypercholesterolemia (HCh), there was a reduction in the efficacy of Ca-pump function of the sarcoplasmic reticulum (SR) of rabbit skeletal muscles, an increase in cholesterol content, and intensification of lipid peroxidation in SR membranes. Supplementation of the cholesterol-rich diet with alpha-tocopherol effectively prevented dysfunction of the SR Ca-pump and reduced the enhanced LPO level in SR membranes without having any effect on cholesterol content in blood serum and SR membranes. The increase in the LPO level seems likely to be primarily responsible for abnormalities in the SR Ca-pump during HCh.

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Martonosi, A.N.; Dux, L.; Taylor, K.A.; Pikula, S. 1988: The Ca2+ pump of skeletal muscle sarcoplasmic reticulum Progress in Clinical and Biological Research 273: 7-14
Arkhipenko, I.V.; Bilenko, M.V.; Dobrina, S.K.; Kagan, V.E.; Kozlov, I.P. 1977: Damage to the sarcoplasmic reticulum of skeletal muscles in leukemia: role of lipid peroxidation Biulleten' Eksperimental'noi Biologii i Meditsiny 83(6): 683-686
Stoĭda, L.V.; Boldyrev, A.A. 1978: Several properties of the Ca-pump of rabbit skeletal muscle sarcoplasmic reticulum in hypercholesteremia Biulleten' Eksperimental'noi Biologii i Meditsiny 86(7): 32-35
Kandarian, S.C.; Peters, D.G.; Taylor, J.A.; Williams, J.H. 1994: Skeletal muscle overload upregulates the sarcoplasmic reticulum slow calcium pump gene American Journal of Physiology 266(5 Pt 1): C1190-C1197
Gubskiĭ, I.I.; Zadorina, O.V.; Fedorov, A.N.; Bogdanova, L.A. 1991: Peroxide modification of skeletal muscle sarcoplasmic reticulum in antioxidant deficiency and under the action of ionol. I. Calcium transport into sarcoplasmic reticulum membranes Ukrainskii Biokhimicheskii Zhurnal 63(4): 81-87
Chernysheva, G.V.; Iliushko, N.A.; Kondrat'ev, I.I.; Mel'nik, V.I.; Stoĭda, L.V. 1982: Effect of 30-day hypokinesia on Ca2+ transport, activity of ATPases and lipid peroxidation in the membranes of the sarcoplasmic reticulum and in the mitochondria of the skeletal and heart muscles Voprosy Meditsinskoi Khimii 28(6): 60-63
Arkhipenko, I.U.; Gazdarov, A.K.; Kagan, V.E.; Kozlov, I.P.; Spirichev, V.B. 1976: Lipid peroxidation and disturbance in Ca2+ transport through sarcoplasmic reticulum membranes during E-avitaminosis Biokhimiia 41(10): 1898-1902
Kagan, V.E.; Azizova, O.A.; Arkhipenko, I.V.; Klaan, N.K.; Kozlov, I.P. 1977: Interrelationship between structural and functional modifications in the membranes of the sarcoplasmic reticulum following lipid peroxidation Biofizika 22(4): 625-630
Deng, H.W.; Kwan, C.Y. 1991: Cyclopiazonic acid is a sarcoplasmic reticulum Ca(2+)-pump inhibitor of rat aortic muscle Zhongguo Yao Li Xue Bao 12(1): 53-58
Aliev, M.K.; Levitskaia, E.L.; Levchenko, T.S.; Levitskiĭ, D.O. 1985: Fractionation of fragments of skeletal muscle sarcoplasmic reticulum according to their sensitivity to caffeine Biokhimiia 50(6): 911-918
Wyskovsky, W.; Suko, J. 1988: Drug-induced calcium release from sarcoplasmic reticulum of skeletal muscle Progress in Clinical and Biological Research 252: 165-169
Voronkov, G.S.; Tsiomik, V.A.; Dubur, G.I. 1986: Relation between the impairment of creatine kinase activity and lipid peroxidation in the membranes of heart mitochondria and sarcoplasmic reticulum in experimental ischemia Ukrainskii Biokhimicheskii Zhurnal 58(1): 72-76
Diadiusha, G.P. 1985: Effect of caffeine on kinetics of accumulation and release of Ca2+ by vesicles of the sarcoplasmic reticulum of skeletal muscle Ukrainskii Biokhimicheskii Zhurnal 57(6): 56-62
Kagan, V.E.; Arkhipenko, I.V.; Kozlov, I.P. 1983: Modification of the enzyme system for Ca2+ transport in sarcoplasmic reticulum membranes during lipid peroxidation. Changes in the chemical composition and ultrastructural organization of the membranes Biokhimiia 48(1): 158-166
Korge, P.; Campbell, K.B. 1994: Local ATP regeneration is important for sarcoplasmic reticulum Ca2+ pump function American Journal of Physiology 267(2 Pt 1): C357-C366
Fantini, G.A.; Yoshioka, T. 1993: Deferoxamine prevents lipid peroxidation and attenuates reoxygenation injury in postischemic skeletal muscle American Journal of Physiology 264(6 Pt 2): H1953-H1959
Lyzlova, L.V.; Persianova, V.R.; Antipenko, A.E.; Lyzlova, S.N. 1987: The increase in viscosity and peroxidation of sarcoplasmic reticulum membrane lipids in isadrine myocarditis Biochemistry International 14(6): 1079-1086
Esyrev, O.V.; Sarsenova, S.S.; Uspanova, Z.K.; Kniazevskaia, I.B.; Turmukhambetova, V.K. 1982: Passive binding of Ca2+ by fragments of the sarcoplasmic reticulum of frog skeletal muscles Voprosy Meditsinskoi Khimii 28(5): 51-55
Tugaĭ, V.A.; Kurskiĭ, M.D.; Diadiusha, G.P.; Zakharchenko, A.N. 1990: The effect of pH on the passive transport of Ca2+ by membranes of fragmented sarcoplasmic reticulum of skeletal muscles Ukrainskii Biokhimicheskii Zhurnal 62(4): 67-71
Khizhniak, S.V.; Voĭtsitskiĭ, V.M.; Kucherenko, N.E. 1991: Structural changes in the sarcoplasmic reticulum membrane of skeletal muscles at the early stage of x-ray irradiation Ukrainskii Biokhimicheskii Zhurnal 63(3): 113-117