Concurrent radiochemotherapy in the treatment of gynaecologic neoplasms
Choo, Y.C.; Choy, T.K.; Wong, L.C.; Ma, H.K.
European Journal of Gynaecological Oncology 6(1): 31-36
1985
ISSN/ISBN: 0392-2936 PMID: 4038649 Document Number: 249738
Chemotherapy with adriamycin and/or cis-platinum in standard dosages concurrent with full radiation produced an accelerated local-regional tumour control leading to complete response in 12 of 14 patients who had advanced primary or recurrent gynecologic neoplasms. The continuation of chemotherapy thereafter did not however prevent the development nor arrest progression of metastases outside the irradiated field. Epidermitis and myelosuppression were the enhanced side effects but were tolerable and manageable. Radiochemotherapy can be applicable in situations where rapid shrinkage of the tumour bulk is required. Its other useful potentials deserve further evaluation.